The2021InternationalConferenceonCyber-physicalSocialIntelligence(CSI)willbeheldinBeijing,China,onDecember18-20,2021.Theconferenceprovidesaninternationalforumforresearchersandpractitionerstoshareinnovativetechnicalandscientificdevelopments,findings,andvisionsinallaspectsofmachineintelligence,humanintelligence,andcyber-physical-socialintelligencerenderedbyvariousinteractionsincyberspace,physicalspace,andsocialspace.Advancesinthosefieldsareofsignificantimportancetowardsinclusive,sustainable,andresilientfutureforpeopleandplanet.